Research Explains How Lead Exposure Produces Learning Deficits

A study of young adult rats by researchers from the Johns Hopkins Bloomberg School of Public Health provides evidence that explains exactly how exposure to lead during brain development produces learning deficits. The study shows that exposure to levels of lead that are similar to those measured in lead-intoxicated children reduces the birth and survival of new neurons (neurogenesis) in the brain. Lead also alters the normal development of newly born neurons in a part of the brain (hippocampus) known to be important for learning and memory. The study is published in the March 30, 2007, issue of Neuroscience.